Mayor of London Sadiq Khan said a "major incident" had been declared.
North Kensington - tower block fire
Forty fire engines and over 200 firefighters and officers have been called to a tower block fire on the Lancaster West estate in north Kensington this morning.
The Brigade has received multiple calls. The fire is from the second floor to the top floor of the 27 floor building.
Assistant Commissioner Dan Daly said: "Firefighters wearing breathing apparatus are working extremely hard in very difficult conditions to tackle this fire. This is a large and very serious incident and we have deployed numerous resources and specialist appliances.“
The Brigade was called at 0054 and is still at the scene. Fire crews from North Kensington, Kensington, Hammersmith and Paddington and from surrounding fire stations are in attendance.
The cause of the fire is not known at this stage.
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